PCR diagnosis of Pneumocystis pneumonia: a bivariate meta-analysis.
نویسندگان
چکیده
We undertook a bivariate meta-analysis to assess the overall accuracy of respiratory specimen PCR assays for diagnosing Pneumocystis pneumonia. The summary sensitivity and specificity were 0.99 (95% confidence interval, 0.96 to 1.00) and 0.90 (0.87 to 0.93). Subgroup analyses showed that quantitative PCR analysis and the major surface glycoprotein gene target had the highest specificity value (0.93). Respiratory specimen PCR results are sufficient to confirm or exclude the disease for at-risk patients suspected of having Pneumocystis pneumonia.
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 49 12 شماره
صفحات -
تاریخ انتشار 2011